Israeli Scientists Use Human Cells to 3D Print Heart

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ChinesePod News - April 17, 2019

Israeli scientists have 3D printed a heart using human tissue cells.  Engineering an organ from the cells of the same patient that needs a transplant could significantly increase the chances of transplantation success.

Vocabulary

雏形prototype

衰竭 failure

移植 transplant

诱导 to induce

兼容性 compatibility

Vocabulary

雛形 prototype

衰竭 failure

移植 transplant

誘導 to induce

兼容性 compatibility

News Transcript

以色列特拉维夫大学的研究员成功以人体组织细胞为材料,透过3D打印技术打造迷你心脏。

这项研究的团队领导人,塔勒‧德维尔博士表示,制作该雏形的技术也可用于日后打印出人体心脏大小的心脏。

使用病患自己的细胞创造心脏能提高移植手术的成功率。在心脏衰竭末期,唯有心脏移植才是有效的治疗手段。

根据有线电视新闻网(CNN)的报导,德维尔表示:「打印材料与患者器官的生化兼容性是降低排斥风险以及移植成功的关键」。

要打印出这个雏形,研究员诱导一名捐赠患者的细胞产出多功能干细胞后,再生成心脏细胞。

接着,他们再使用该心脏矩阵,制成用来打印的个体化凝胶。

该研究目前还在进行中,德维尔博士的团队计划训练打印出的心脏开始跳动,再将打印的心脏移植至动物身上,最终可望用于人体。

News Transcript

以色列特拉維夫大學的研究員成功以人體組織細胞為材料,透過3D打印技術打造迷你心臟。

這項研究的團隊領導人,塔勒‧德維爾博士表示,製作該雛型的技術也可用於日後打印出人體心臟大小的心臟。

使用病患自己的細胞創造心臟能提高移植手術的成功率。在心臟衰竭末期,唯有心臟移植才是有效的治療手段。

根據有線電視新聞網(CNN)的報導,德維爾表示:「打印材料與患者器官的生化兼容性是降低排斥風險以及移植成功的關鍵」。

要列印出這個雛形,研究員誘導一名捐贈患者的細胞產出多功能幹細胞後,再生成心臟細胞。

接著,他們再使用該心臟矩陣,製成用來列印的個體化凝膠。

該研究目前還在進行中,德維爾博士的團隊計畫訓練打印出的心臟開始跳動,再將打印的心臟移植至動物身上,最終可望用於人體。

Researchers at Tel Aviv University have 3D printed a miniature heart using a patient’s tissue cells.

Dr. Tal Dvir, who led the research team, noted that the same technology used to print the prototype could be used to print human hearts to size.

Use of a patient’s own cells to engineer organs could improve the success rate of heart transplantation, which is the only means of treatment for end-stage heart failure.

CNN reported that, according to Dvir, "The biocompatibility of engineered materials is crucial to eliminating the risk of implant rejection, which jeopardizes the success of such treatments."

To create the prototype, the researchers reprogrammed a donor patient’s cells as stem cells, which differentiated into heart cells.

The scientists then used the cellular matrix to form a personalized hydrogel for printing.

In their ongoing research, Dr. Dvir’s team plans to train printed hearts to form pumping ability. The researchers will then transplant printed organs into animals and eventually into humans.

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